At first you might think "How the heck can a state have so many regulations!?". Even the ~40000 regulations of the states with the least regulations might seem like a lot. How the heck are people supposed to be able to keep track of all those regulations so they can avoid violating them?But if you look closer there is a hint to what is going on. According to the US News article these are the 10 most regulated states: California, New York, Ohio, Illinois, Texas, Oregon, Washington, Florida, Massachusetts, Louisiana.
These are the 10 least regulated: South Carolina, Michigan, Wyoming, Kansas, Arizona, Nevada, Montana, North Dakota, South Dakota, Idaho.
Note: the US News article says they had to omit some states due to limited availability of data. Also that list is from 6 years ago. I found a later list without those omissions.
It is mostly the same, with the addition of some of the states the US News list had to skip, and the order is quite a different in the two bottom 10 lists.
Combining the lists these are the most regulated states (in alphabetical order): California, Colorado, Florida, Illinois, Louisiana, Massachusetts, New Jersey, New York, Ohio, Oregon, Texas, and Washington.
These are the least regulated: Alaska, Arizona, Idaho, Kansas, Michigan, Minnesota, Montana, Nevada, North Dakota, South Carolina, South Dakota, Utah, Wyoming.
One thing that stands out about the first list is that most of them are major players in a variety of major industries. The second list doesn't seem to be nearly as diversified.
I bet if you dove into the details of regulations this would be a big factor. The top list has more regulations simply because they have more to regulate. In any given field they don't necessarily have more regulations than other states, but they have more fields that are big enough to need regulation. More diversity also means more conflict between different industries which will tend to increase the need for regulation.
A key aspect of this, and why we aren't overwhelmed with just keeping up with regulations, is it is the breadth of the regulatory systems that leads to the high counts. not the depth. You only have to deal with a few branches in this wide tree.
For example the US News article says that the most regulated industry is administrative and support services, such as unemployment services, collection agencies, and call centers. All of us not involved in such services can pretty much ignore that big chunk of regulation.
There is a similar thing with the federal tax code. The Internal Revenue Code is around 7000 pages, and the Federal Tax Regulations are another ~70000 pages. But a lot of that is because of the breadth of the US economy, and another contributor to the size is that the government uses per industry tax incentives and penalties as a way to encourage or discourage things that they want to influence. The net result is the tax code and regulations are full of things that 99% of taxpayers (individual and business) can completely ignore.